The San Fernando Valley is known for its association with the entertainment and media industry. The region has film studios, production facilities, and related businesses, contributing to job creation in the sector.

Healthcare and education are significant contributors to the economy of the San Fernando Valley. The region is home to hospitals, medical centers, and educational institutions that support job opportunities in these fields. Ventura has a focus on health and wellness, with businesses related to spas, fitness, and wellness services. This sector may contribute to job creation in the area. Santa Barbara is a popular tourist destination known for its beaches, Spanish architecture, and cultural attractions. The tourism and hospitality industry supports a significant number of jobs in the city.

The technology sector has been growing in the San Fernando Valley, Ventura and Santa Barbara, with a focus on startups, software development, and innovation. Effort to promote tech entrepreneurship contribute to job opportunities. The presence of the University of California, Santa Barbara (UCSB), contributes to research and development activities.